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  • Showing 1-11 of 11 Results
2016
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.de Waal, L., Lewis TA, Rees MG, Tsherniak A., Wu X., Choi PS, Gechijian L., Hartigan C., Faloon PW, Hickey MJ, Tolliday N., Carr SA, Clemons PA, Munoz B., Wagner BK, Shamji AF, Koehler AN, Schenone M., Burgin AB, Schreiber SL, et al. Nature chemical biology, 2016/02/01, Volume 12, Issue 2, p.102-8, (2016) Read More / View Supplemental Materials
Abstract
2015
Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2015/10/22, Volume 526, Issue 7574, p.596, (2015) Read More / View Supplemental Materials
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.Begun, J., Lassen KG, Jijon HB, Baxt LA, Goel G., Heath RJ, Ng A., Tam JM, Kuo SY, Villablanca EJ, Fagbami L., Oosting M., Kumar V., Schenone M., Carr SA, Joosten LA, Vyas JM, Daly M. J., Netea MG, Brown GD, et al. Cell reports, 2015/06/30, Volume 11, Issue 12, p.1905-18, (2015) Read More / View Supplemental Materials
Abstract
Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.Chou, DH, Vetere A., Choudhary A., Scully SS, Schenone M., Tang A., Gomez R., Burns SM, Lundh M., Vital T., Comer E., Faloon PW, Dančík V., Ciarlo C., Paulk J., Dai M., Reddy C., Sun H., Young M., Donato N., et al. Journal of the American Chemical Society, 2015/06/24, Volume 137, Issue 24, p.7929-34, (2015) Read More / View Supplemental Materials
Abstract
2014
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells.Krönke, J., Udeshi ND, Narla A., Grauman P., Hurst SN, McConkey M., Svinkina T., Heckl D., Comer E., Li X., Ciarlo C., Hartman E., Munshi N., Schenone M., Schreiber SL, Carr SA, and Ebert BL Science (New York, N.Y.), 2014/01/17, Volume 343, Issue 6168, p.301-5, (2014) Read More / View Supplemental Materials
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2013
Target identification and mechanism of action in chemical biology and drug discovery.Schenone, M., Dančík V., Wagner BK, and Clemons PA Nature chemical biology, 2013/04/01, Volume 9, Issue 4, p.232-40, (2013) Read More / View Supplemental Materials
Abstract
2012
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.Wen, Q., Goldenson B., Silver SJ, Schenone M., Dancik V., Huang Z., Wang LZ, Lewis TA, An WF, Li X., Bray MA, Thiollier C., Diebold L., Gilles L., Vokes MS, Moore CB, Bliss-Moreau M., VerPlank L., Tolliday NJ, Mishra R., et al. Cell, 2012/08/03, Volume 150, Issue 3, p.575-89, (2012) Read More / View Supplemental Materials
Abstract
Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.Ong, SE, Li X., Schenone M., Schreiber SL, and Carr SA Methods in molecular biology (Clifton, N.J.), 2012/01/01, Volume 803, p.129-40, (2012) Read More / View Supplemental Materials
Abstract
2011
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2011/07/13, Volume 475, Issue 7355, p.231-4, (2011) Read More / View Supplemental Materials
Abstract
2009
Empirical Bayes analysis of quantitative proteomics experiments.Margolin, AA, Ong SE, Schenone M., Gould R., Schreiber SL, Carr SA, and Golub T. R. PloS one, 2009/10/14, Volume 4, Issue 10, p.e7454, (2009) Read More / View Supplemental Materials
Abstract
Identifying the proteins to which small-molecule probes and drugs bind in cells.Ong, SE, Schenone M., Margolin AA, Li X., Do K., Doud MK, Mani D. R., Kuai L., Wang X., Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub T. R., Gould RJ, Schreiber SL, and Carr SA Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4617-22, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results