'Lnc'-ing enhancers to MYC regulation.
Cell Res
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Abstract | Long noncoding RNAs (lncRNAs) are emerging as important functional components in the establishment of long-range chromosomal interactions. In a recent paper published in Cell Research, Xiang et al. provide mechanistic insight into this phenomenon by characterizing the role of CCAT1-L, a colorectal cancer-specific lncRNA, in intra-chromosome looping between the MYC gene promoter and distal upstream enhancer elements that regulate MYC transcription. |
Year of Publication | 2014
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Journal | Cell Res
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Volume | 24
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Issue | 6
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Pages | 643-4
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Date Published | 2014 Jun
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ISSN | 1748-7838
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URL | |
DOI | 10.1038/cr.2014.54
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PubMed ID | 24777251
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PubMed Central ID | PMC4042177
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