Therapeutic insights from genomic studies of head and neck squamous cell carcinomas.

Cancer Discov
Authors
Keywords
Abstract

Large and comprehensive genomic surveys of head and neck squamous cell carcinomas (HNSCC) are now greatly increasing our understanding of the diversity of this disease and the key genomic changes that drive these tumors. The results from these studies are beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we review some of the key findings from recent genomic studies of head and neck cancers, including the most comprehensive study to date from The Cancer Genome Atlas Network.

Year of Publication
2015
Journal
Cancer Discov
Volume
5
Issue
3
Pages
239-44
Date Published
2015 Mar
ISSN
2159-8290
URL
DOI
10.1158/2159-8290.CD-14-1205
PubMed ID
25643909
PubMed Central ID
PMC4355279
Links
Grant list
UL1 TR000005 / TR / NCATS NIH HHS / United States
K08 CA163677 / CA / NCI NIH HHS / United States
R01 CA098372 / CA / NCI NIH HHS / United States
P50 CA097190 / CA / NCI NIH HHS / United States
R01 DE023685 / DE / NIDCR NIH HHS / United States